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Author Topic: Odd Of Virus Breakthrough On TX?  (Read 664 times)

Offline jeremyc

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Odd Of Virus Breakthrough On TX?
« on: January 10, 2012, 03:11:45 PM »
Currently on tx with victrelis  . Start Vl 21.2 mil  week 4 <43 week 8 und week 12 und, Just took week 24 pcr yesterday very nervous as this is last Vl test before EOT. What are the odds of Vieus breathrough now? Ive been 110% compliant on my tx
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Offline hepcatts

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Re: Odd Of Virus Breakthrough On TX?
« Reply #1 on: January 10, 2012, 03:26:57 PM »
Jeremy,  I've been doing Incivek, and the clinical trials statistics for that one depend a lot on treatment history i.e. starting out naive vs. previous relapser vs. non-responder. On Incivek, in my case, every UND increases the odds of SVR/cure. I bet the trials results probably were similar for victrellis. Reply with your specifics and one of the resident experts can probably give you the exact (statistical) numbers. On Incivek if you started naive, you are already in the 90%+ range for SVR.    Kirk
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Offline jeremyc

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Re: Odd Of Virus Breakthrough On TX?
« Reply #2 on: January 10, 2012, 03:29:38 PM »
treament naive first time.
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Offline alice

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Re: Odd Of Virus Breakthrough On TX?
« Reply #3 on: January 10, 2012, 03:38:14 PM »
Jeremy... viral breakthrough typically happens with people who do not respond well to interferon. You appear to respond very well to tx. I would not worry about this if i were you. (and that's saying something cuz I'm a worrywart  :grin:)

alice
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Offline hepcatts

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Re: Odd Of Virus Breakthrough On TX?
« Reply #4 on: January 10, 2012, 03:42:39 PM »
GR,Keith, etc. will reply soon with the real numbers, but I bet you're okay
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Offline jeremyc

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Re: Odd Of Virus Breakthrough On TX?
« Reply #5 on: January 10, 2012, 03:48:14 PM »
Thanks guys its very hard playing the waiting game lol lab said ill know tommorow
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Offline banarep

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Re: Odd Of Virus Breakthrough On TX?
« Reply #6 on: January 10, 2012, 06:27:04 PM »
Quote
Among nonblack boceprevir recipients whose HCV RNA levels became undetectable by week 8 (60%) and those with undetectable HCV RNA levels through week 24 (47%), the rate of sustained virologic response was 97%


http://www.nejm.org/doi/full/10.1056/NEJMoa1010494#t=articleResults

97% chance of SVR
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Offline jeremyc

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Re: Odd Of Virus Breakthrough On TX?
« Reply #7 on: January 10, 2012, 07:32:01 PM »
Wow prayin im clear tommorow.!!!
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Offline keith

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Re: Odd Of Virus Breakthrough On TX?
« Reply #8 on: January 10, 2012, 08:42:26 PM »
I agree with Kirk and BR, i think your in the 90% + range for SVR
 Think positive Bro!!!
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Offline jeremyc

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Re: Odd Of Virus Breakthrough On TX?
« Reply #9 on: January 11, 2012, 06:33:30 PM »
Und were the results @ Week 24 im so happy today!!!
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Offline keith

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Re: Odd Of Virus Breakthrough On TX?
« Reply #10 on: January 11, 2012, 07:56:19 PM »
Awesome news,  congrats :)
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Online New York Sue

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Re: Odd Of Virus Breakthrough On TX?
« Reply #11 on: January 11, 2012, 07:58:18 PM »
 :fairydust:  :fairydust:  :fairydust:
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Offline greyrocker

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Re: Odd Of Virus Breakthrough On TX?
« Reply #12 on: January 11, 2012, 08:50:25 PM »
Great news, Jeremy!  :cool:

greyrocker
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Offline jeremyc

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Re: Odd Of Virus Breakthrough On TX?
« Reply #13 on: January 11, 2012, 09:11:34 PM »
Thanks guys a new life is what im looking forward to just4 more shots
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Offline banarep

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Re: Odd Of Virus Breakthrough On TX?
« Reply #14 on: January 12, 2012, 12:04:12 AM »
good for you.  so glad to hear.
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