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Author Topic: greyrocker update - 16 weeks post-tx  (Read 1219 times)

Offline greyrocker

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greyrocker update - 16 weeks post-tx
« on: September 16, 2010, 05:26:25 PM »
At 16 weeks post tx, I am 2/3 of the way to the 24 week mark and my next VL.  I had what I think was some really good news today. I had some bloodwork done the other day and the results were that everything is normal; liver enzymes, hgb, ferritin, uric acid, etc. Now I know that this is not a definitive indicator of SVR, but I feel real good about things. It's nice to know that everything seems to be functioning as it should.

My other good news is that this week I started full-time at the detox where I've been working for the past near 5 years. I had been part-time but an opening came up and I was next in line. This is real significant; it just makes my life easier in a lot of ways. I've had to resign my other job counselling at an addiction recovery home, but this was what I wanted. There's also some other possibilities on the horizon, so all in all, life is good!

A have a lot of gratitude for this site, and most importantly, for all the members.

 :cool:
greyrocker
And as we let our own light shine, we unconsciously give other people permission to do the same. Nelson Mandela
        SVR as of Dec. 08, 2010

Offline ipaqgps

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Re: greyrocker update - 16 weeks post-tx
« Reply #1 on: September 16, 2010, 08:06:28 PM »
GreyRocker,

Congrats!! Nice when things come together to help make life easier! I am so excited for you and your future. Both in your vl test and work!

Love it 2/3 of the way there...but whose counting?   :whistling:

I think we all here are very happy to have YOU!

ipaq
 :)
Geno 3a Tx start date 9/8/10  end date 11/30/10 vl 2.3 mill  UND @ 1 week
Clinical Trial Pharmasett PSI-7977 400 mg and 180 mg. interferon

Offline Postcard

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Re: greyrocker update - 16 weeks post-tx
« Reply #2 on: September 16, 2010, 10:29:15 PM »
Most excellent all around, my friend! After a long, tired road, things appear to be clicking along for you.  I couldn't be happier for you!  I am anxious to hear about life working one job.  I still can't believe that you were working 10+ days in a row while on tx.....jeesh!  You are a machine!!!!  Keep that positive attitude and just let it flow!  SVR for you?  No doubt!

Keep on truckin'....

postcard  :cool:
Good people do good things over the long haul. - Tom Hanks

Offline banarep

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Re: greyrocker update - 16 weeks post-tx
« Reply #3 on: September 16, 2010, 10:36:11 PM »
Rocker that is great news.  And while it is not a viral load test, I am sure it is saying SVR.  I am very happy for you and your family.   :lol: :grin: :) :cool: :cool: :cool: :cool:
I hate to advocate drugs, alcohol, or insanity to anyone, but they've always worked for me.    Hunter S. Thompson

Offline greyrocker

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Re: greyrocker update - 16 weeks post-tx
« Reply #4 on: September 17, 2010, 01:02:45 AM »
Thanks ipaq!  :grin:

BR and PC and me, the 3 amigos....one day, we will sit down together, break bread, compare war wounds.....and see who can one-up the others with bs!  :devil:

Thanks for being my bro's.
 :cool:
GR
And as we let our own light shine, we unconsciously give other people permission to do the same. Nelson Mandela
        SVR as of Dec. 08, 2010

Offline pixie

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Re: greyrocker update - 16 weeks post-tx
« Reply #5 on: September 17, 2010, 01:48:35 AM »
Well done Rocker..

Sustained Virological Response at 12 Weeks Post-treatment May be as Good as 24 Weeks for Determining Interferon Cure

Sustained virological response (SVR) to hepatitis C treatment is usually defined as continued undetectable HCV viral load 24 weeks after completion of therapy. Michelle Martinot-Peignoux and colleagues from France evaluated whether assessment of serum HCV RNA 12 weeks after the end of treatment was as relevant as 24 weeks for determining SVR.

The investigators analyzed sustained treatment outcomes among 573 chronic hepatitis C patients who received pegylated interferon (Pegasys or PegIntron) plus ribavirin and had an end-of-treatment virological response. Viral load was measured using a sensitive TMA assay with a lower limit of 5-10 IU/mL. Viral relapse was defined as reappearance of detectable HCV-RNA between the end of treatment and post-treatment week 24.

Results

All 573 participants had undetectable HCV RNA at the end of treatment.
At 12 weeks post-treatment, 409 participants still had undetectable viral load.
At 24 weeks post-treatment, 408 participants (71%) achieved SVR.
Looking back at week 12 results, all but 1 of the patients who were undetectable at week 12 remained so at week 24.
Week 12 response had a positive predictive value of 99.7% for predicting Week 24 SVR.

The researchers concluded that assessment of serum HCV RNA 12 weeks after the end of treatment using a highly sensitive TMA assay "is as relevant as after 24 weeks to predict SVR and make decisions on the management of treated patients, suggesting a new definition for SVR."

Institut National de la Santé et de la Recherche Médicale, Centre de Recherche Biomédicale Bichat-Beaujon CRB3, Université Paris VII, Paris, France; Service d'Hépatologie, Hopital Beaujon, Clichy, France.

6/11/10

Reference
M Martinot-Peignoux, C Stern, S Maylin, and others. Twelve weeks posttreatment follow-up is as relevant as 24 weeks to determine the sustained virologic response in patients with hepatitis C virus receiving pegylated interferon and ribavirin. Hepatology 51(4):1122-1126 (Abstract). April 2010.

Source: www.hivandhepatitis.com

Offline sweet sue

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Re: greyrocker update - 16 weeks post-tx
« Reply #6 on: September 17, 2010, 07:21:25 AM »
Gr, I'm so happy to hear that recovery is well on it's way.

However you do fail to mention that while on tx working two jobs that you also kept up the Heralding News, contributed to the newsletter and were the Global Moderator.

I'm glad to hear that you are down to one full time job.

BTW, how's your little Bella doing?

sweet sue  :fairydust:
Avenge yourself, live long enough to be a problem to your children.

Offline greginky

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Re: greyrocker update - 16 weeks post-tx
« Reply #7 on: September 17, 2010, 07:34:42 AM »
Great to hear GR
Not all who wander are lost.~~~~~ J.R.R. Tolkien

Offline jimmer

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Re: greyrocker update - 16 weeks post-tx
« Reply #8 on: September 17, 2010, 07:44:11 AM »
Good news GR, blood test looks good, job situation looks good, you got the sparkle in your eye. Wish you well my friend.

jimmer

Offline Malisa

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Re: greyrocker update - 16 weeks post-tx
« Reply #9 on: September 17, 2010, 08:25:19 AM »
Greyrocker, Nice to hear about your job and labs. Sounds like life post treatment is agreeing with you.  :happy:

Keep on rockin'

Malisa

Offline rjs

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Re: greyrocker update - 16 weeks post-tx
« Reply #10 on: September 17, 2010, 08:36:44 AM »
GR,

You have been a rock for so many on this site.  Very happy that life is coming together for you.

1/2 way down... that is just AWESOME!!  I have to believe that your labwork is indicative of that SVR!

Take Care,
rjs

P.S.  Can we vidoetape your BS session with BR and PC so we can post it on the site??   It may be one of the most inspiring (and comical)  :whistling: :wink: videos we would have!  :tongue:
Geno 1a Treated during acute phase for 24 weeks SVR 5/2011

Offline banarep

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Re: greyrocker update - 16 weeks post-tx
« Reply #11 on: September 17, 2010, 10:40:12 AM »
Rocker,

I vote for PC on the bs.   :devil:
I hate to advocate drugs, alcohol, or insanity to anyone, but they've always worked for me.    Hunter S. Thompson

Offline greyrocker

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Re: greyrocker update - 16 weeks post-tx
« Reply #12 on: September 17, 2010, 01:46:48 PM »
Rocker,

I vote for PC on the bs.   :devil:

Me too, after all, it certainly would NOT be me or you, now would it?  :angel:

 :devil: :devil:
GR
And as we let our own light shine, we unconsciously give other people permission to do the same. Nelson Mandela
        SVR as of Dec. 08, 2010

Offline jimmer

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Re: greyrocker update - 16 weeks post-tx
« Reply #13 on: September 17, 2010, 04:16:52 PM »
Rocker,

I vote for PC on the bs.   :devil:

Me too, after all, it certainly would NOT be me or you, now would it?  :angel:

 :devil: :devil:
GR

 :angel:  :lol:

Offline Postcard

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Re: greyrocker update - 16 weeks post-tx
« Reply #14 on: September 17, 2010, 07:28:27 PM »
Heeeeeeeeeeyyyyyyyy!!!!!!!!!  (thought I should at least pretend to be insulted and hurt!)

I vote for me as well.  After all, I have an MFA in acting!   :angel:  (I am also pretty much full of "it."   :devil:

postcard  :cool:
Good people do good things over the long haul. - Tom Hanks

 

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